Mechanisms of Macular Degeneration
نویسندگان
چکیده
منابع مشابه
Mechanisms of Macular Degeneration
The 12th Annual Vision Research Conference, ‘‘Mechanisms of Macular Degeneration” was held at the Convention Center at Ft. Lauderdale, Florida, May 1–2, 2009. The meeting reviewed the latest developments in the genetics of AMD, and focused on animal models that closely mimic early or late onset human macular diseases. Major areas covered were mechanisms that lead to macular dystrophies, phenoty...
متن کاملMechanisms of Age-Related Macular Degeneration
Age-related macular degeneration (AMD), a progressive condition that is untreatable in up to 90% of patients, is a leading cause of blindness in the elderly worldwide. The two forms of AMD, wet and dry, are classified based on the presence or absence of blood vessels that have disruptively invaded the retina, respectively. A detailed understanding of the molecular mechanisms underlying wet AMD ...
متن کاملMolecular mechanisms of subretinal fibrosis in age-related macular degeneration.
Subretinal fibrosis is a result of a wound healing response that follows choroidal neovascularization in neovascular age-related macular degeneration (nAMD). Although anti-vascular endothelial growth factor therapy has become a standard treatment that improves visual acuity in many nAMD patients, unsuccessful treatment outcomes have often been attributed to the progression of subretinal fibrosi...
متن کاملthe genetics of age-related macular degeneration
age-related macular degeneration (amd) is the leading cause of blindness in old subjects. it is a multifactorial disease with both environmental and genetic factors playing some role in its pathogenesis. similar to many other genetic diseases, the inheritance pattern of amd does not fit into simple mendelian rules. these diseases are caused by the presence of multiple genetic factors and are ca...
متن کاملDry age-related macular degeneration: mechanisms, therapeutic targets, and imaging.
Age-related macular degeneration is the leading cause of irreversible visual dysfunction in individuals over 65 in Western Society. Patients with AMD are classified as having early stage disease (early AMD), in which visual function is affected, or late AMD (generally characterized as either "wet" neovascular AMD, "dry" atrophic AMD or both), in which central vision is severely compromised or l...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Vision Research
سال: 2010
ISSN: 0042-6989
DOI: 10.1016/j.visres.2010.02.007